Medically reviewed by Drugs.com. Last updated on Oct 21, 2019.
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- A lightweight serum that saturates the skin with a concentrated boost of hydration. Prep + Prime Moisture Infusion MAC Cosmetics - Official Site arrow-down icon.
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- Side Effects
A lightweight serum that saturates the skin with a concentrated boost of hydration, making it a unique hybrid between skincare and priming. Gently soothes, revives and replenishes the skin while preparing it for foundation. Usage:. After cleansing, apply a desired amount to fingertips and blend over the face, then use your daily moisturizer if desired. MAC is working toward a cruelty-free.
For the Consumer
Applies to propofol: parenteral injectable emulsion
- Microbial Contamination
- Propofol injectable emulsion can support microbial growth.1 (See Potential for Microbial Contamination under Cautions.)
- Use strict aseptic technique at all times during handling; failure to use aseptic technique may result in microbial contamination and possible fever, infection/sepsis, other life-threatening illness, and/or death.12103113194195197198199
- Discard unused portions within the required time limits.12 (See Stability and Sterility Considerations under Dosage and Administration.)
- Do not use if contamination is suspected.12194
Side effects include:
Use for anesthesia or MAC sedation: Bradycardia, arrhythmia, tachycardia, hypotension, hypertension, movement, burning/stinging, pain at injection site, apnea, rash, pruritus.
Use for critical care setting sedation: Bradycardia, decreased cardiac output, hypotension, hyperlipidemia, respiratory acidosis (during weaning).
For Healthcare Professionals
Applies to propofol: intravenous emulsion
Very common (10% or more): Hypotension (75%)
Common (1% to 10%): Hypertension, bradycardia
Uncommon (0.1% to 1%): Arrhythmias, atrial fibrillation, atrioventricular heart block, bigeminy, bundle branch block, cardiac arrest, ECG abnormal, edema, extrasystole, heart block, myocardial infarction, myocardial ischemia, premature ventricular contractions, ST segment depression, supraventricular tachycardia, tachycardia, ventricular fibrillation, extrasystole, syncope, chest pain, right heart failure
Rare (0.01% to 0.1%): Pulmonary edema, asystole, syncope, perioperative arrhythmias, cardiac arrest
Very rare (less than 0.01%): Cardiac failure
Frequency not reported: Cardiac arrhythmia[Ref]
Very common (10% or more): Pruritus (28%)
Common (1% to 10%): Transient flush, rash
Uncommon (0.1% to 1%): Conjunctival hyperemia, diaphoresis, urticaria[Ref]
Common (1% to 10%): Nausea, vomiting
Uncommon (0.1% to 1%): Hypersalivation, cramping, diarrhea, dry mouth, enlarged parotid, nausea, impaired swallowing, vomiting, ileus
Very rare (less than 0.01%): Pancreatitis, abdominal cramps[Ref]
Uncommon (0.1% to 1%): Urinary retention oliguria
Rare (Less than 0.1%): Discoloration of the urine following prolonged use[Ref]
Frequency not reported: Hepatomegaly[Ref]
Rare (0.01% to 0.1%): Anaphylaxis, in some cases with angioedema, bronchospasm, erythema, and hypotension (these reactions have been reported to respond to adrenaline)[Ref]
Common (1% to 10%): Pain during injection (e.g., burning, tingling/slinging)
Serato scratch live free download for windows 8. Very rare (less than 0.01%): Tissue necrosis following accidental extravascular administration
Uncommon (0.1% to 1%): Hives/itching, phlebitis, redness/discoloration[Ref]
Uncommon (0.1% to 1%): BUN Increased, creatinine increased, dehydration, hyperglycemia, metabolic acidosis, osmolality increased
Very rare (less than 0.01%): Metabolic acidosis, hyperkalemia, hyperlipidemia[Ref]
Uncommon (0.1% to 1%): Pain in extremities, trunk pain, whole body weakness, pain in extremities, neck rigidity/stiffness
Very rare (less than 0.01%): Rhabdomyolysis (when administered at doses greater than 4 mg/kg/hour for ICU sedation)[Ref]
Paresthesias (including burning, tingling, stinging) and/or pruritus, usually manifested in the perineal region, were the most frequently recorded adverse reactions in clinical trials. Paresthesias and pruritus generally occurred within 5 minutes after administration of the initial dose and were generally transient and mild to moderate in intensity. The pharmacologic basis of these sensory phenomena is unknown. No pretreatments, including the use of nonsteroidal anti-inflammatory drugs, opioids, or lidocaine, are known to have an effect on or to reduce the incidence of these sensations.[Ref]
Very common (10% or more): Paresthesia (74%), excitation phenomena such as involuntary movements, twitches, tremors, hypertonus, hiccup
Common (1% to 10%): Headache, shivering
Rare (0.01% to 0.1%): Convulsions and seizures of the epileptic type
Very rare (less than 0.01%): Postoperative unconsciousness
Frequency not reported: Involuntary movements[Ref]
Very common (10% or more): Hypoxemia (11%)
Common (1% to 10%): Procedural pain (bronchoscopy), transient apnea, cough, respiratory acidosis during weaning
Uncommon (0.1% to 1%): Bronchospasm, burning in throat, cough, dyspnea, hiccough, hyperventilation, hypoventilation, hypoxia, laryngospasm, pharyngitis, sneezing, tachypnea, upper airway obstruction, apnea
Very rare (less than 0.01%): Pulmonary edema[Ref]
Very rare (less than 0.01%): Renal failure[Ref]
Common (1% to 10%): Thrombosis, phlebitis
Uncommon (0.1% to 1%): Hemorrhage, coagulation disorder, leukocytosis[Ref]
Uncommon (0.1% to 1%): Sepsis[Ref]
Uncommon (0.1% to 1%): Diplopia, eye pain, nystagmus[Ref]
Common (1% to 10%): Elation/euphoria
Frequency not reported: Drug abuse and dependence[Ref]
Uncommon (0.1% to 1%): Fever, anticholinergic syndrome, ear pain, taste perversion, tinnitus[Ref]
1. 'Product Information. Propofol (propofol).' Hospira Inc, Lake Forest, IL.
2. 'Product Information. Diprivan (propofol).' Zeneca Pharmaceuticals, Wilmington, DE.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
More about propofol
- During Pregnancy or Breastfeeding
Other brands:Diprivan, Propoven